J HEPATOL
2011年11月01日-
Journal of Hepatology 2011 VOL. 55 NO. 5分享 ()
本期看点
1.在慢性肝病患者中,肝脏精确硬度预测门脉高压相关的并发症:前瞻性研究
2.血色素沉着病基因与非酒精性脂肪肝:系统回顾及综合分析
3.全速奔跑增强HCV治疗应答:期待,但要慎重
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Research Articles-Viral Hepatitis
乙型肝炎病毒X蛋白是感染后引起并维持病毒复制的要素
Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection
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在聚乙二醇干扰素+利巴韦林再治疗的HCV-1非应答患者中,病毒动力学用于早期预测持续病毒应答的有用性
Usefulness of viral kinetics for early prediction of a sustained virological response in HCV-1 non-responders re-treated with pegylated interferon and ribavirin
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IL28B多态性预测慢性丙肝患者治疗第一天HCVRNA减少
IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C
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达诺瑞韦/利托纳韦+聚乙二醇干扰素α-2a/利巴韦林治疗丙肝患者的抗病毒活性、安全性及药代动力学
Antiviral activity, safety, and pharmacokinetics of danoprevir/ritonavir plus PEG-IFN α-2a/RBV in hepatitis C patients
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柑桔素通过PPAR介导机制抑制传染性丙肝病毒颗粒集聚和长期复制
Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism
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Research Articles-Cirrhosis
在慢性肝病患者中,肝脏精确硬度预测门脉高压相关的并发症:前瞻性研究
Liver stiffness accurately predicts portal hypertension related complications in patients with chronic liver disease: A prospective study
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Toll样受体2促进剂和内含子2多态性与肝硬化特发性细菌性腹膜炎的风险增加相关
Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis
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肝硬化用拉埃内克纤维化评分系统的组织学分级与临床阶段和门脉高压程度相关
Histological subclassification of cirrhosis using the Laennec fibrosis scoring system correlates with clinical stage and grade of portal hypertension
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Research Articles-Cancer
引起免疫缺陷的HIV与肝癌的高风险相关:1998-2008法国ANRS CO3 Aquitaine 队列研究
HIV-induced immune deficiency is associated with a higher risk of hepatocarcinoma, ANRS CO3 Aquitaine Cohort, France, 1998–2008
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在多数HBV相关肝细胞癌的移植患者群体中,“地铁车票”预报者的确认
Validation of the “Metroticket” predictor in a cohort of patients transplanted for predominantly HBV-related hepatocellular carcinoma
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在缺少相同器官(SIAH)-1 中,遍在蛋白连接酶7的细胞核表达诱导肝癌细胞的增殖和转移
Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells
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在肝细胞癌中,信号传导子及转录激活子3是索拉菲尼的主要激酶独立靶点
Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma
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临床前的多参数成像用于预测栓塞术后肝细胞癌坏死的确认
Validation of preclinical multiparametric imaging for prediction of necrosis in hepatocellular carcinoma after embolization
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Research Articles-Molecular and Cell Biology
至于两种细胞核受体配体诱导的小鼠肝细胞增殖,c-jun的表达不是强制性的:TCPOBOP与T3
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3
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Research Articles- Genetic and Metabolic Diseases
在代谢综合征的肥胖小鼠中,静脉给予多能间质细胞预防非酒精性脂肪性肝炎的发生
Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome
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肝活检在诊断中的作用与酒精性肝硬化急性恶化患者的预后
The role of liver biopsy in the diagnosis and prognosis of patients with acute deterioration of alcoholic cirrhosis
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在早期非酒精性脂肪肝的鼠模型中,胰岛素耐药与肝脏微循环
Insulin resistance and liver microcirculation in a rat model of early NAFLD
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在高胆固醇的小鼠中,白细胞介素1α或白细胞介素1β的缺乏抑制脂肪变性向脂肪性肝炎的转化和肝纤维化
Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
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血色素沉着病基因与非酒精性脂肪肝:系统回顾及综合分析
Hemochromatosis gene and nonalcoholic fatty liver disease: A systematic review and meta-analysis
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Research Articles- Liver Failure and Growth
1982-2007法国泡型包虫病的演化与临床特征:387例患者的观察结果
Clinical features and evolution of alveolar echinococcosis in France from 1982 to 2007: Results of a survey in 387 patients
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Reviews
“肝脏的城市”:肝脏之现代名称起源于宗教仪式,美食及政治
“The city of Hepar”: Rituals, gastronomy, and politics at the origins of the modern names for the liver
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乙型肝炎表面抗原量化:为什么?2011如何用?核心组报告
Hepatitis B surface antigen quantification: Why and how to use it in 2011 – A core group report
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Special Sections-International Hepatology
全速奔跑增强HCV治疗应答:期待,但要慎重
A sprint to increase response to HCV treatment: Expectancies but caution
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在HCV感染调节先天免疫反应期间,展开的蛋白反应和自体吞噬的活化
Activation of unfolded protein response and autophagy during HCV infection modulates innate immune response
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在出现静脉曲张破裂出血的肝硬化高危患者中,早期隐蔽支架的TIPS:我们准备好跳入水池深处了吗?
Early TIPS with covered stents in high-risk patients with cirrhosis presenting with variceal bleeding: Are we ready to dive into the deep end of the pool?
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Special Sections- Frontiers in Liver Transplantation
HCC之肝移植的标准:应限制什么?
Criteria for liver transplantation for HCC: What should the limits be?
期刊简介
《Journal of Hepatology》是欧洲肝病学会的官方杂志。该杂志发表原始论文、评论、案例报告及与编辑沟通的书信。该杂志是英文出版。欧洲肝病学会成立于1966年4月,宗旨是在世界范围内促进肝病研究,提高肝病的治疗水平。不仅欧洲国家的医生可以接受其肝病相关继续教育课程,而且发展中国家的医生也可以参加这些课程的学习。...[点击查看全部简介]
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