Journal of Hepatology 2012 VOL. 56 NO. 1

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Research Articles-Viral Hepatitis

在Con A诱导的肝炎中，IL-33/ST2轴的保护作用

Protective role of IL-33/ST2 axis in Con A-induced hepatitis

在丙肝病毒基因1型患者对聚乙二醇干扰素/利巴韦林联合治疗24周反应的鉴定中，白细胞介素-28B遗传性变体

Interleukin-28B genetic variants in identification of hepatitis C virus genotype 1 patients responding to 24 weeks peginterferon/ribavirin

体外筛选与HCV复制子特征对多样非核苷聚合酶抑制剂耐药

In vitro selection and characterization of HCV replicons resistant to multiple non-nucleoside polymerase inhibitors

在HIV/HCV双重感染的患者中，基于干扰素治疗对肝纤维化进展的影响：回顾性重复肝活检分析

Influence of interferon-based therapy on liver fibrosis progression in HIV/HCV coinfected patients: A retrospective repeated liver biopsy analysis

在慢性丙型肝炎中，肝纤维化之9次血检与瞬时弹性成像的比较： ANRS HCEP-23研究

Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: The ANRS HCEP-23 study

在导致缩短表面蛋白的HBV基因C型表面基因中，密码子182的核苷酸变化与肝病进展相关

Nucleotide change of codon 182 in the surface gene of hepatitis B virus genotype C leading to truncated surface protein is associated with progression of liver diseases

在慢性丙肝患者的肝脏中，先天抗病毒应答的定向损害

Targeted impairment of innate antiviral responses in the liver of chronic hepatitis C patients

在日本，特拉瑞韦+聚乙二醇干扰素+利巴韦林用于HCV基因1型慢性感染患者初次治疗

Telaprevir with peginterferon and ribavirin for treatment-naive patients chronically infected with HCV of genotype 1 in Japan

Research Articles-Cirrhosis

在自发性细菌性腹膜炎中，全球细菌DNA检测之新的原位杂交方法的开发提供细菌感染的早期证据

Development of a new in situ hybridization method for the detection of global bacterial DNA to provide early evidence of a bacterial infection in spontaneous bacterial peritonitis

进入ICU的肝硬化患者预后评分的前瞻性评估

Prospective evaluation of the prognostic scores for cirrhotic patients admitted to an Intensive Care Unit

在代偿性肝硬化和潜在可切除肝肿瘤患者中，瞬时弹性成像对门脉高压的评估

Assessment of portal hypertension by transient elastography in patients with compensated cirrhosis and potentially resectable liver tumors

在门腔静脉吻合鼠中，鸟氨酸乙酸苯酯预防肠道血液产生的运动诱发电位紊乱

Ornithine phenylacetate prevents disturbances of motor-evoked potentials induced by intestinal blood in rats with portacaval anastomosis

Research Articles-Cancer

在肝细胞癌和Child-Pugh A级肝硬化患者中，射频消蚀后的存活与移植补救

Survival after radiofrequency ablation and salvage transplantation in patients with hepatocellular carcinoma and Child-Pugh A cirrhosis

循环microRNA-21作为肝细胞癌的新奇生物标记

Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma

GNAS激活的突变经STAT3活话定义炎症性肝肿瘤特征的罕见亚群

GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation

在体外和体内的原发性肝细胞癌中，mTORC1/C2 复合体的二元靶向作用增强组蛋白脱乙酰酶抑制剂介导的抗肿瘤效应

Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

Research Articles-Molecular and Cell Biology

Cdc42和Rac1是肝细胞内向饱和性脂肪酸刺激的JNK途径之主要贡献者

Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes

学科分类：192-198, January 2012,

在肝脏的葡萄糖反应中，ChREBP的活化需要6-磷酸葡萄糖，而不是5-磷酸木酮糖

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

为了CAR调节的肝细胞增生与药物代谢需要SRC-3

SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism

Research Articles-Cholestasis and Autoimmune Diseases

在原发性胆汁性肝硬化中，吸烟作为肝纤维化的独立性风险因素

Smoking as an independent risk factor of liver fibrosis in primary biliary cirrhosis

Research Articles- Genetic and Metabolic Diseases

在病态肥胖中，慢性间歇性缺氧是非酒精性脂肪肝的主要触发因素

Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese

在大量前瞻性初级保健群体中，非酒精性脂肪肝的存在与严重性

Presence and severity of non-alcoholic fatty liver disease in a large prospective primary care cohort

血清蛋白组学分析显示血红蛋白用于非酒精性脂肪肝的诊断价值

Serum proteomic analysis revealed diagnostic value of hemoglobin for nonalcoholic fatty liver disease

小鼠配体依赖性辅阻遏物充当甲状腺激素受体和抑制肝脏脂肪生成的新奇辅阻遏物

Ligand-dependent corepressor acts as a novel corepressor of thyroid hormone receptor and represses hepatic lipogenesis in mice

Research Articles- Transplantation

肝移植之后，外周血HDVRNA早期迅速下降，而延长的肝内肝炎δ抗原持续

Rapid early HDV RNA decline in the peripheral blood but prolonged intrahepatic hepatitis delta antigen persistence after liver transplantation

Research Articles- Liver Failure and Growth

在重症患儿中，高氨血症毒性的开端

Threshold for toxicity from hyperammonemia in critically ill children

急性肝损伤/急性肝衰竭对止血法作为凝血弹性描记术评估的最小作用

Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography

鞘氨醇激酶-2抑制改善线粒体功能及肝脏缺血-再灌注后的存活

Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia–reperfusion

在小鼠脂肪肝中，Rho抑制剂预防缺血-再灌注损伤

Rho inhibitor prevents ischemia–reperfusion injury in rat steatotic liver

FGL2/Fibroleukin通过诱导小鼠窦状内皮细胞和肝细胞的细胞凋亡介导肝的再灌注损伤

FGL2/Fibroleukin mediates hepatic reperfusion injury by induction of sinusoidal endothelial cell and hepatocyte apoptosis in mice

Reviews

生活方式干预用于成人非酒精性脂肪肝的治疗：系统回顾

Lifestyle interventions for the treatment of non-alcoholic fatty liver disease in adults: A systematic review

肝细胞癌(HCC)的分子诊断与治疗：科技进展的新领域

Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): An emerging field for advanced technologies

Case Report

线粒体翻译延伸因子EFTs突变致严重的婴儿肝衰竭

Mutation in the mitochondrial translation elongation factor EFTs results in severe infantile liver failure