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尽管有诸多的指南供临床医师参考，但是临床上仍存在着很多困惑，如醒后卒中是否可以选择溶栓治疗？年龄超过80岁和儿童是否可以选择溶栓治疗？症状反复波动的患者是否可以溶栓治疗？

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Ischemic stroke during sleep: its association with worse early functional o...

出处： Stroke; a journal of cerebral circulation.2011-07;42(7):1901-6

Wake-up stroke: clinical and neuroimaging characteristics.

出处： Cerebrovascular diseases (Basel, Switzerland).2010;29(4):336-42

The stroke patient who woke up: clinical and radiological features, includi...

出处： Stroke; a journal of cerebral circulation.2002-04;33(4):988-93

Safety and effectiveness of endovascular therapy after 8 hours of acute isc...

出处： Stroke; a journal of cerebral circulation.2009-10;40(10):3269-74

Population-based study of wake-up strokes.

出处： Neurology.2011-05-10;76(19):1662-7

Thrombolytic therapy for patients who wake-up with stroke.

出处： Stroke; a journal of cerebral circulation.2009-03;40(3):827-32